New York City, a major city in the state of New York, was where the main offices of the Global Weekly were located, and where Buck Williams had lived. It was also the former location of the United Nations before Nicolae Carpathia changed the organization into Global Community and moved it to New Babylon.
In "Tribulation Force", it was reported that New York City was destroyed in the missile attack of World War III with the second Seal Judgment. However, it is mentioned again in "Glorious Appearing", indicating that it either had survived or was rebuilt. (A third explanation could be that it was simply a continuity error in the story series.)